Frontiers in Public Health
Introduction: Tetanus vaccine coverage in Vietnam has been declining in recent years due to a rapid population growth rate, shrinking budget, and inecient resource mobilization strategy. This study examined the uptake, demand, and willingness to pay (WTP) for tetanus vaccines in Vietnamese women of reproductive age as well as determined associated factors and assessed the feasibility of the long-term tetanus vaccine resource mobilization scheme. Methods: Cross-sectional data were obtained on 807 women of childbearing age in Hanoi, Vietnam in 2016. Tetanus vaccine uptake, demand, and willingness to pay were collected by using a structured questionnaire. Multivariable logistic and interval regression models were used to examine associated factors with vaccine uptake, demand, and WTP. Results: Of 807 participants, 42.4 and 64.8% had sucient tetanus vaccination (i.e., received at least three doses of vaccine) and were willing to pay for tetanus vaccination. The mean amount of WTP for one dose of tetanus was US$ 7.3 (95% CI = 6.7–7.9). Having children or being aware that the tetanus vaccine was free-of-charge were negatively associated with WTP for tetanus vaccine. Having a high school education, living in a rural area, and not being aware of vaccine prices or being aware that vaccines were provided freely reduced the amount of WTP. WTP increased among women receiving information from friends and relatives. Conclusion: Despite of exemption from the tetanus vaccination programs, this study indicated a low tetanus vaccination coverage and a moderate degree of WTP for tetanus vaccine among Vietnamese women of childbearing age. Frontiers in Public Health 01 frontiersin.org Nguyen et al. 10.3389/fpubh.2022.980850 Target-specific educational and financial support interventions, along with e
The association between selective serotonin reuptake inhibitor (SSRI) treatment and lower bone mineral density (BMD) remains controversial, and further research is required. This study aimed to compare the BMD, levels of bone formation and bone metabolism markers in medicated premenopausal Singaporean women with major depressive disorder (MDD) and matched healthy controls. We examined 45 women with MDD who received SSRI treatment (mean age: 37.64 ± 7) and 45 healthy controls (mean age: 38.1 ± 9.2). BMD at the lumbar spine, total hip and femoral neck were measured using dual-energy X-ray absorptiometry. We also measured bone formation markers, procollagen type 1 N-terminal propeptide (P1NP) and bone metabolism markers, osteoprotegerin (OPG) and receptor activator of nuclear factor-kappa-B ligand (RANKL). There were no significant differences in the mean BMD in the lumbar spine (healthy controls: 1.04 ± 0.173 vs. MDD patients: 1.024 ± 0.145, p = 0.617, left hip (healthy controls: 0.823 ± 0.117 vs. MDD patients: 0.861 ± 0.146, p = 0.181) and right hip (healthy controls: 0.843 ± 0.117 vs. MDD patients: 0.85 ± 0.135, p = 0.784) between healthy controls and medicated patients with MDD. There were no significant differences in median P1NP (healthy controls: 35.9 vs. MDD patients: 37.3, p = 0.635), OPG (healthy controls: 2.6 vs. MDD patients: 2.7, p = 0.545), RANKL (healthy controls: 23.4 vs. MDD patients: 2178.93, p = 0.279) and RANKL/OPG ratio (healthy controls: 4.1 vs. MDD patients: 741.4, p = 0.279) between healthy controls and medicated patients with MDD. Chronic SSRI treatment might not be associated with low BMD in premenopausal Singaporean women who suffered from MDD. This finding may help female patients with MDD make an informed decision when considering the risks and benefits of SSRI treatment.
Early diagnosis of major depressive disorder (MDD) could enable timely interventions and effective management which subsequently improve clinical outcomes. However, quantitative and objective assessment tools for the suspected cases who present with depressive symptoms have not been fully established.
Le Thi Huong, Thao Thi Phuong, Nguyen Corey Jacinto, Cuong Tat Nguyen, Linh Gia Vu, Hien Thu Nguyen, Minh Ngoc Le Vu, Xuan Thi Thanh Le, Thao Thanh Nguyen, Quan Thi Pham, Nhung Thi Kim Ta, Quynh Thi Nguyen, Carl A Latkin, Cyrus SH Ho, Roger CM Ho
Risk Management and Healthcare Policy
Purpose: New COVID-19 variants pose great challenges in protecting the success of vaccination programs. Awareness of community
becomes an important component to prevent the spread of COVID-19. This study aims to analyze people’s awareness of COVID-19
and identify the implications for optimal risk communication in Vietnam.
Study Methods and Materials: A total of 341 individuals participated in an online cross-sectional study. Community awareness on
COVID-19 was examined by using a structured questionnaire. Multivariable Tobit regression was used to examine associated factors
with community awareness.
Results: Our results indicated high levels of awareness of local COVID-19 situation, transmission risks, and preventive behavioral
practices during the first week of social isolation. Higher awareness of local pandemic situation was associated with female
respondents (Coef.: 6.19; 95% CI: 0.51; 11.87) and larger family sizes of above 5 people (Coef.: 9.00; −1.00; 19.00). Respondents
between 35–44 years old were shown to be less aware of preventive behavioral practices than other age groups, including the group of
participants above 44 years old (Coef.: −0.34; 95% CI: −0.67; −0.02). Lastly, participants who were “fairly satisfied” with information
resources had awareness levels of preventive behavioral practices lower than that of “unsatisfied” respondents (Coef.: −0.45; 95% CI:
0.74; −0.16).
Conclusion: This study offers crucial insights into the pandemic awareness of citizens and risk communication effectiveness during
COVID-19 in Vietnam. The study findings shall serve the development of policies and interventions aimed at empowering individuals
in the local and global fight against coronavirus
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