Frontiers in Tropical Diseases
The COVID-19 global pandemic has been going on for more than two years, and the evolution of SARS-CoV-2 with many variants of concern still poses a risk to public health. Sufficient access to qualified and validated testing plays an important role in detecting and alerting trends of the pandemic and provides evidence for making decisions in preventive strategies and policies. Depending on the method of testing and laboratory conditions, validation parameters (i.e., analytical sensitivity, limit of detection, diagnostic sensitivity, analytical specificity, diagnostic specificity, repeatability, reproducibility, robustness, positive predictive value, negative predictive value, applicability, practicability, and time to results) can be very different. With three main types of COVID-19 detection kits available, comprising nucleic acid, serological, and antigen detection, the kind of validation parameters that should be used becomes a complicated consideration and takes time to assess. Our review provides valuable and comprehensive information for laboratories in the assessment and selection of the optimal parameters to validate new COVID-19 test kits.
Tạp chí Y học dự phòng
To validate the Vietnamese version Internet Gaming Disorder-20 (VN-IGD-20) Test for teenagers, a survey among 349 gamers, who were accepted in the interview, from secondary and high schools from 28 game stores was conducted in Hanoi, Vietnam. The IGD-20 Test comprised 20 items with six different dimensions, using a 5-point Likert scale. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were used to examine the validation; Cronbach’s Alpha was performed to test the reliability; and Latent class analysis (LCA) was applied to identify the level of internet gaming disorder (IGD). Moreover, the ROC curve diagram was used with the highest Youden’s Index parameter to determine the best cut-off point. CFA proved that the VN-IGD-Test with 17 items, which was divided into five-factor dimensions. The model indexes of the Vietnamese questionnaire included RMSEA = 0.053; SRMR = 0.052; GFI = 0.929; TLI = 0.908 and CFI = 0.927. The values for Cronbach’s alpha coefficient of each dimension ranged from 0.823 to 0.840. The LCA found out four levels of IGD: casual gamers, regular gamers, low-risk engaged gamers, and high-risk engaged gamers. Additionally, the optimal empirical cut-off point with the highest Youden’s Index was 47.5 (out of 85). The present study findings illustrated that the VN-IGD-17 Test could be used as a valid and reliable tool for assessing internet gaming disorder in Vietnamese teenagers.
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