Sang M. Nguyen, Huong T.T. Tran, Lan M. Nguyen, Oanh Thi Bui, Dong V. Hoang, Martha J. Shrubsole, Qiuyin Cai, Fei Ye, Wei Zheng, Hung N. Luu, Thuan V. Tran, Xiao-Ou Shu
Cancer Epidemiology, Biomarkers & Prevention
Background: Evidence on associations between dietary intake and risk of breast cancer subtypes is limited and inconsistent. We evaluated associations of fruit, vegetable, meat, and fish consumption with risk of breast cancer overall and by molecular subtype in the Vietnamese Breast Cancer Study (VBCS). Method: VBCS includes 476 incident breast cancer cases and 454 age-matched controls. Dietary habits over the past 5 years were assessed by in-person interviews using a validated food frequency questionnaire. Associations of food groups with breast cancer were evaluated via logistic regression for overall and molecular subtype with adjustment for age, education, income, family history of cancer, menopausal status, body mass index, exercise, total energy intake, and other potential dietary confounders. Odds ratio (OR) was used to approximate relative risk. Results: High fruit intake was inversely associated with breast cancer risk, with adjusted ORs [95% confidence intervals (CI)] of 0.67 (95% CI, 0.47–0.95) and 0.41 (95% CI, 0.27–0.61) for second and third tertiles versus first tertile, respectively (Ptrend < 0.001). This association was stronger for triple-negative than other subtypes (Pheterogeneity < 0.001). High intake of freshwater fish was inversely associated with overall breast cancer (ORT3vsT1 ¼ 0.63; 95% CI, 0.42–0.95; Ptrend ¼ 0.03). An inverse association was observed between HER2-enriched subtype and red and organ meat intake (ORT3vsT1¼0.40; 95% CI, 0.17–0.93;Ptrend¼0.04;Pheterogeneity¼0.50). Conclusions: High intakes of fruit and freshwater fish were associated with reduced breast cancer risk; association for the former was stronger for triple-negative subtype. Impact: Our findings suggest high intakes of fruit and freshwater fish may reduce breast cancer risk among Vietnamese women.
Lam Duc Nguyen, Long Hoang Nguyen, Ly Thi Ninh, Ha Thu Thi Nguyen, Anh Duy Nguyen, Linh Gia Vu, Hao Si Anh Nguyen, Son Hoang Nguyen, Linh Phuong Doan, Thuc Minh Thi Vu, Bach Xuan Tran, Carl A. Latkin, Cyrus S. H. Ho, Roger C. M. Ho
BMC Pregnancy and Childbirth
Background: Self-care behaviors during pregnancy signifcantly impacts mother and children’s health. This study aimed to explore the self-care behaviors and the associations of these behaviors with the psychological well-being of women during pregnancy, as well as the mediating efects of diferent social support with these associations. Methods: A cross-sectional data of 562 pregnant women at Hanoi Obstetrics & Gynecology Hospital and Ca Mau Obstetrics & Pediatrics in Vietnam were analyzed. Questions about self-care behaviors, pregnancy characteristics, social support, and psychological well-being were asked. Multivariate regression models were performed. Structural Equation Modeling (SEM) was employed to test the mediating efects of diferent social support with the association between self-care behaviors and psychological well-being. Findings : Only 13% of pregnant women often or always did physical exercise at least three times a week, and 40% consumed enough fber and fve servings of vegetables a day. Only 78.7% always avoided alcohol drinking, and 53.9% of pregnant women avoided being exposed to second-hand smoking and 71,7% avoided using traditional medicine without physicians’ prescriptions. Around 66% of pregnant women always or often had prenatal care checkups as scheduled. Information sources, social support and childbirth expectation were major drivers for self-care practices. SEM model showed that social support mediated the relationship between maternal health behaviors and mental well-being. Conclusion: This study highlighted the remarkable gaps in self-care practices among our pregnant women, which were signifcantly associated with their mental well-being. Social support-oriented consultancy and interventions should be warranted for improving behaviors and the mental well-being of pregnant women in Vietnam. Keywords: Maternal behavior, Psychological well-being, Social support, Pregnant women, Structural equation modeling
Huyen Phuc Do, Thang Van Vo, Linda Murray, Philip R.A. Baker, Aja Murray, Sara Valdebenito, Manuel Eisner, Bach Xuan Tran, Bao-Yen Luong-Thanh, Lan Hoang Nguyen, Michael P. Dunne
Child Abuse & Neglect
Background: Despite the detrimental effects and life-course health consequences of violence exposure, relatively few studies have adequate capacity to investigate the evolution of violence from childhood to motherhood. Objective: This study aims to examine the cyclical nature of childhood abuse and prenatal interpartner violent victimization (p-IPV) and its adverse impact on childbirth trauma and exclusive breastfeeding (EBF) practice in Vietnam. Method: Using a prospective birth cohort, 150 pregnant women were recruited in the third trimester of pregnancy in Hue city in central Vietnam (Wave 1-Baseline) and re-interviewed approximately three months after delivery (Wave 2-Follow-up). The direct and indirect effects of violent victimization on subsequent childbirth experience (measured by Birth Memories and Recall Questionnaire) and EBF practice were estimated by using augmented-inverse-probabilityweighted models, sensitivity analysis, and structural equation model. Results: Detrimental and prolonged effects of the inter-generational cycle of violence transverse childhood to motherhood. Women who experienced either childhood abuse or p-IPV violence were more likely to experience negative emotional childbirth memories [ARR 1.21, 95 % CI (1.04, 1.39)]. Evidence also suggested that not continuing to exclusively breastfeed at 3 months post-partum was strongly associated with prenatal depression, young age, and perceived low social status during pregnancy. Perceived strong connectedness among extended family members and social networks (i.e. nexus among family, friends, and neighborhood) provided a buffering
effect by preventing EBF termination.
Conclusion: This research provides insights into the protective role of social connectedness in
improving breastfeeding practice. It is vital to establish wholistic antenatal care and social service
system to offer specialized support and response for victims of violence and mitigate the longterm sequelae of traumatic events.
The association between selective serotonin reuptake inhibitor (SSRI) treatment and lower bone mineral density (BMD) remains controversial, and further research is required. This study aimed to compare the BMD, levels of bone formation and bone metabolism markers in medicated premenopausal Singaporean women with major depressive disorder (MDD) and matched healthy controls. We examined 45 women with MDD who received SSRI treatment (mean age: 37.64 ± 7) and 45 healthy controls (mean age: 38.1 ± 9.2). BMD at the lumbar spine, total hip and femoral neck were measured using dual-energy X-ray absorptiometry. We also measured bone formation markers, procollagen type 1 N-terminal propeptide (P1NP) and bone metabolism markers, osteoprotegerin (OPG) and receptor activator of nuclear factor-kappa-B ligand (RANKL). There were no significant differences in the mean BMD in the lumbar spine (healthy controls: 1.04 ± 0.173 vs. MDD patients: 1.024 ± 0.145, p = 0.617, left hip (healthy controls: 0.823 ± 0.117 vs. MDD patients: 0.861 ± 0.146, p = 0.181) and right hip (healthy controls: 0.843 ± 0.117 vs. MDD patients: 0.85 ± 0.135, p = 0.784) between healthy controls and medicated patients with MDD. There were no significant differences in median P1NP (healthy controls: 35.9 vs. MDD patients: 37.3, p = 0.635), OPG (healthy controls: 2.6 vs. MDD patients: 2.7, p = 0.545), RANKL (healthy controls: 23.4 vs. MDD patients: 2178.93, p = 0.279) and RANKL/OPG ratio (healthy controls: 4.1 vs. MDD patients: 741.4, p = 0.279) between healthy controls and medicated patients with MDD. Chronic SSRI treatment might not be associated with low BMD in premenopausal Singaporean women who suffered from MDD. This finding may help female patients with MDD make an informed decision when considering the risks and benefits of SSRI treatment.
Tạp chí nghiên cứu Y học
Sexual dysfunction is common during pregnancy. This disorder will continue and worsened during the postpartum period, greatly affecting family happiness. The objective of the study was to access the effectiveness of communication and counseling interventions to improve sexual function of pregnant women. We used Female Sexual Functuin Function Index to assess sexual dysfunction for pregnant women. The study’s results showed that the FSFI score in the control group decreased by -2.5 (IQR: -7.2 to 0.2) points while in the intervention group, the decrease was only -1.1 (IQR: -5 to 2.6) points. This difference is statistically significant with p < 0.05. In the intervention group, pregnant woman who did not read media books or read less than 20% had the same reduction in FSFI scores after 1 month as the control group. The higher the reading level, the better the FSFI score. The risk of no intercourse during pregnancy in the control group was 2.81 times higher (95% CI 1.26 - 6.29) than in the intervention group. There was 64.0% of reduction in the risk of not having intercourse in the intervention group in comparison with the control group
Lê Thị Thanh Xuân, Xuan Thi Thanh Le, Nguyen Thao Thi Nguyen, Huong Thi Le, Toan Thanh Thi Do, Thang Huu Nguyen, Huong Lan Thi Nguyen, Trang Ha Nguyen, Linh Gia Vu, Bach Xuan Chan, Carl A. Latkin
Global Health: Science and practice
Long Hoang Nguyen, Men Thi Hoang, Lam Duc Nguyen, Ly Thi Ninh, Ha Thi Thu Nguyen, Anh Duy Nguyen, Giang Thu Vu, Linh Phuong Doan, Carl A Latkin, Bach Xuan Tran, Cyrus S H Ho, Roger C M Ho
Tropical Medicine & International Health
Objectives: The aim of this study was to assess acceptance of COVID-19 vaccination and the willingness to pay (WTP) for it, and investigate associated factors among pregnant women in Vietnam.
Methods: Cross-sectional survey of pregnant women in two obstet
Xuan Thi Thanh Le, Phuong Thi Ngoc Nguyen, Toan Thi Thanh Do, Thang Huu Nguyen, Huong Thi Le, Cuong Tat Nguyen, Giang Hai Ha, Chi Linh Hoang, Bach Xuan Tran, Carl A. Latkin, Roger C.M. Ho, Cyrus S.H. Ho
International Journal of Environmental Research and Public Health
This study aimed to describe mental health service utilization and examine associated factors among students in Vietnam. Data were collected at eight universities in Hanoi, Vietnam, in 2018 using an administered questionnaire. The total number of participants was 9,120 (95.1% response rate). Among stu dents participating in our survey, 12.5% (95% CI: 10.9–14.1) with depression and/or anxiety symptoms used mental health service in the last 12 months. In the multivariable regression models, significant factors associated with mental health ser vice utilization were marital status, types of housemate, men tal health problems, physical activity, smoking status, and alcohol drinking. Our study made recommendations to stake holders for improving mental health services utilization among students in Vietnam. These findings had important implica tions for future research on factors associated with mental health service utilization among university students.
Toan Thanh Thi Do, Anh Ngoc Nguyen Xuan Thanh Thi Le, Ann Pongsakul, Quang Nhat Nguyen, Thanh Van Nguyen, Thang Huu Nguyen, Tri Minh Do, Huong Thi Le, Huong Lan Thi Nguyen, Nu Thi Truong, Chi Linh Hoang, Giang Thu Vu, Tung Thanh Tran, Tung Hoang Tran, Bach Xuan Tran, Carl A. Latkin, Cyrus SH Ho, Roger CM Ho
International Journal of Environmental Research and Public Health
This study aimed to describe mental health service utilization and examine associated factors among students in Vietnam. Data were collected at eight universities in Hanoi, Vietnam, in 2018 using an administered questionnaire. The total number of participants was 9,120 (95.1% response rate). Among stu dents participating in our survey, 12.5% (95% CI: 10.9–14.1) with depression and/or anxiety symptoms used mental health service in the last 12 months. In the multivariable regression models, significant factors associated with mental health ser vice utilization were marital status, types of housemate, men tal health problems, physical activity, smoking status, and alcohol drinking. Our study made recommendations to stake holders for improving mental health services utilization among students in Vietnam. These findings had important implica tions for future research on factors associated with mental health service utilization among university students.
National Institute for Health Research
This study aimed to describe mental health service utilization and examine associated factors among students in Vietnam. Data were collected at eight universities in Hanoi, Vietnam, in 2018 using an administered questionnaire. The total number of participants was 9,120 (95.1% response rate). Among stu dents participating in our survey, 12.5% (95% CI: 10.9–14.1) with depression and/or anxiety symptoms used mental health service in the last 12 months. In the multivariable regression models, significant factors associated with mental health ser vice utilization were marital status, types of housemate, men tal health problems, physical activity, smoking status, and alcohol drinking. Our study made recommendations to stake holders for improving mental health services utilization among students in Vietnam. These findings had important implica tions for future research on factors associated with mental health service utilization among university students.
Xuan Thi Thanh Le, Phuong Thi Ngoc Nguyen, Toan Thi Thanh Do, Thang Huu Nguyen, Huong Thi Le, Cuong Tat Nguyen, Giang Hai Ha, Chi Linh Hoang, Bach Xuan Tran, Carl A. Latkin, Roger C.M. Ho, Cyrus S.H. Ho
International Journal of Environmental Research and Public Health
This study aimed to describe mental health service utilization and examine associated factors among students in Vietnam. Data were collected at eight universities in Hanoi, Vietnam, in 2018 using an administered questionnaire. The total number of participants was 9,120 (95.1% response rate). Among stu dents participating in our survey, 12.5% (95% CI: 10.9–14.1) with depression and/or anxiety symptoms used mental health service in the last 12 months. In the multivariable regression models, significant factors associated with mental health ser vice utilization were marital status, types of housemate, men tal health problems, physical activity, smoking status, and alcohol drinking. Our study made recommendations to stake holders for improving mental health services utilization among students in Vietnam. These findings had important implica tions for future research on factors associated with mental health service utilization among university students.
CLINICAL MEDICINE
This study aimed to describe mental health service utilization and examine associated factors among students in Vietnam. Data were collected at eight universities in Hanoi, Vietnam, in 2018 using an administered questionnaire. The total number of participants was 9,120 (95.1% response rate). Among stu dents participating in our survey, 12.5% (95% CI: 10.9–14.1) with depression and/or anxiety symptoms used mental health service in the last 12 months. In the multivariable regression models, significant factors associated with mental health ser vice utilization were marital status, types of housemate, men tal health problems, physical activity, smoking status, and alcohol drinking. Our study made recommendations to stake holders for improving mental health services utilization among students in Vietnam. These findings had important implica tions for future research on factors associated with mental health service utilization among university students.
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