Tài liệu số - Xem chi tiết



Smoking trajectory and cancer risk: A population-based cohort study
Minji Han, Tra T. Bui, Phuong Thao T. Tran, Min-Kyung Lim, Jin K. Oh
INTRODUCTION Smoking behavior can change with time and lead to different health outcomes. This study explored the trajectory of smoking and its relationship with cancer incidence and mortality among Korean male adults. METHODS We used 2002–2018 data from the National Health Insurance Service (NHIS). Smoking status was repeatedly measured in four waves of general health examinations provided by the NHIS between 2002 and 2009. Cancer incidence and mortality were tracked from 2010 to 2018. Trajectory analysis was used to identify the patterns of smoking. The hazard ratio was calculated using Cox proportional regression models. RESULTS For the 2448548 men (≥20 years), 137788 cases of cancers and 41146 cancer deaths were found. We identified six trajectory groups: never smokers, former smokers, new current smokers, decreasing light smokers, steady moderate smokers, and steady heavy smokers. All smoking groups had an increased risk of cancer. The steady heavy smokers showed higher cancer incidence and mortality rate than the steady non-smokers (hazard ratio, HR=1.53; 95% CI: 1.49–1.58 and HR=2.64; 95% CI: 2.50–2.79, respectively). The cancer-specific analysis showed that the larynx and lung cancer incidence and mortality rate of the smoking group were higher than in never smokers. CONCLUSIONS Smoking, even at low doses, increases the risk of most cancers in men. Quitting or reducing smoking, especially at a young age, can lower cancer incidence and mortality. This study may provide more objective results on the relationship between smoking and cancer, because smoking behavior was examined at multiple time points.
2022
10p
eng
Tobacco Induced Diseases
71
20
Xem trailer
Đăng nhập tài khoản vào hệ thống để được xem toàn văn tài liệu.
Danh sách tệp tin điện tử
NoFileNameViewsDownloadsDownload
1. 2022YHDPTCQT037.pdf
Thông tin chia sẻ
Lượt xem:  0 Lượt tải:  0
Chia sẻ: 
Bình chọn:  Điểm bình chọn: 
0
Loại tài liệu số:  - Bài báo
- Bài báo quốc tế
Thảo luận

Đăng nhập

Đăng nhập     Quên mật khẩu
Tích hợp đăng nhập với
  |  Google
Chưa có tài khoản? Đăng ký

Thống kê

Thư viện số

Loại tài liệu số

    THỐNG KÊ TRUY CẬP

    3.398.279

    110.375

    Liên kết website